PEX1 Monoclonal antibody, PBS Only

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  WB analysis using 67436-1-Ig (same clone as 67436-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67436-1-Ig (PEX1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67436-1-PBS in a different storage buffer formulation.

PEX1 Monoclonal Antibody for WB, Indirect ELISA

Cat No. 67436-1-PBS

Clone No.2F3H5

Host / Isotype

Mouse / IgG2b

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

2F3H5, EC:3.6.4.-, Peroxin 1, Peroxin-1, Peroxisomal ATPase PEX1

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Product Information

67436-1-PBS targets PEX1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Mouse / IgG2b
• Class: Monoclonal
• Type: Antibody
• Immunogen: PEX1 fusion protein Ag4623
• Full Name: peroxisomal biogenesis factor 1
• Calculated Molecular Weight: 1283 aa, 143 kDa
• Observed Molecular Weight: 143 kDa
• GenBank Accession Number: BC035575
• Gene Symbol: PEX1
• Gene ID (NCBI): 5189
• RRID: AB_2882673
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: O43933
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

Peroxin (PEX) proteins generate and maintain peroxisomes. The peroxin-1 (PEX1) ATPase facilitates the recycling of the peroxisome matrix protein receptor PEX5 and is the most commonly affected peroxin in human peroxisome biogenesis disorders (PMID: 28600347).  PEX1 and PEX6 are the only members of the AAA family (for ATPases associated with diverse cellular) activities implicated in peroxisome biogenesis and are closely related to p97, which functions in endoplasmic reticulum-associated protein degradation to retrotranslocate endoplasmic reticulum proteins to the cytosol (PMID: 9695811; 11740563).