Product Information
26366-1-PBS targets PAR1/Thrombin Receptor in WB, IHC, ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | PAR1/Thrombin Receptor fusion protein Ag24378 Predict reactive species |
Full Name | coagulation factor II (thrombin) receptor |
Calculated Molecular Weight | 47 kDa |
Observed Molecular Weight | 70 kDa |
GenBank Accession Number | BC051909 |
Gene Symbol | F2R |
Gene ID (NCBI) | 2149 |
RRID | AB_2880492 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P25116 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Protease-activated receptor-1 (PAR1) is a G protein coupled receptor.PAR1 has a greater affinity for thrombin and mediates rapid Ca2+ mobilization and platelet activation. PAR1 has a calculated molecular weight of 47 kDa, but can be detected as 70 kDa after posttranslational modification.(PMID: 26822533)