P glycoprotein Monoclonal antibody, PBS Only

P glycoprotein Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 67258-2-PBS
Clone No.1G6C2

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, IHC, IF/ICC, Indirect ELISA

ABCB1, 1G6C2, EC:7.6.2.2, EC:7.6.2.1, ATP-dependent translocase ABCB1

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

67258-2-PBS targets P glycoprotein in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen P glycoprotein fusion protein Ag17811 Predict reactive species
Full Name ATP-binding cassette, sub-family B (MDR/TAP), member 1
Calculated Molecular Weight 1280 aa, 142 kDa
Observed Molecular Weight130-150 kDa
GenBank Accession NumberBC130424
Gene Symbol P glycoprotein
Gene ID (NCBI) 5243
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP08183
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

ABCB1 (also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer. For optimal WB detection, we recommend to avoid boiling the sample after lysis.

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