NeutraKine®HGF Monoclonal antibody, PBS Only

NeutraKine®HGF Monoclonal Antibody for Neutralization, ELISA

Cat No. 69027-1-PBS
Clone No.2D2B4

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

HGF, HGF Alpha, 2D2B4, Hepatocyte growth factor, Hepatocyte growth factor alpha chain

Formulation:  PBS Only
Sterile PBS
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


69027-1-Ig

Product Information

69027-1-PBS targets NeutraKine®HGF in applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen human HumankineHGF protein HZ-1084 Predict reactive species
Full Name hepatocyte growth factor (hepapoietin A; scatter factor)
Gene Symbol HGF
Gene ID (NCBI) 3082
Conjugate Unconjugated
Purification MethodProtein G purification
Storage Buffer PBS Only, pH 7.4.
Storage ConditionsStore at -80°C.

Background Information

Hepatocyte growth factor (HGF) is the most potent mitogen of mature hepatocytes in primary culture. HGF is derived from a biologically inactive single chain precursor of 728 amino acids (pro-HGF) localized mostly on the cell surface and in the extracellular matrix. The mature form produced following proteolytic cleavage is composed of a 69-kDa α-subunit (containing four kringle domains) and the 34 kDa β-subunit, similar to the catalytic domain of serine proteases, but with amino acid substitutions in the active site. HGF is a pleiotropic cytokine which exerts a variety of effects on several cells, being involved in the regulation of many biological processes, such as inflammation, tissue repair, morphogenesis, angiogenesis, tumour propagation, immunomodulation of viral infections and cardio-metabolic activities.

This antibody is used to neutralize the bioactivity of HGF.

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