Anti-Human Neuropilin 1/CD304 Rabbit Recombinant Antibody, PBS Only

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  FC experiment of HUVEC using 98210-1-RR (same clone as 98210-1-PBS)

  1x10^6 HUVEC cells (left) or MCF-7 cells (right) were surface stained with 0.25 ug Anti-Human Neuropilin 1/CD304 Rabbit Recombinant Antibody (98210-1-RR, Clone: 241812B11) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98210-1-PBS in a different storage buffer formulation.

Neuropilin 1/CD304 Uni-rAb^TM Recombinant Antibody for FC

Cat No. 98210-1-PBS

Clone No.241812B11

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Synonyms

neuropilin 1, NRP1, Neuropilin-1, CD304, BDCA4

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Product Information

98210-1-PBS targets Neuropilin 1/CD304 in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant protein
• Full Name: neuropilin 1
• GenBank Accession Number: BC007533
• Gene Symbol: Neuropilin 1
• Gene ID (NCBI): 8829
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: O14786
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Neuropilin 1 (NRP1), also known as CD304 or VEGF165R, is a type I transmembrane proteins consisting of a small intracellular cytoplasmic domain, a transmembrane domain and an extracellular domain containing a complement-binding CUB domain (a1/a2), a coagulation factor V/VIII (b1/b2) domain, and a meprin or MAM domain (PMID: 24263240; 11886873). It is expressed on plasmacytoid dendritic cells (pDCs), endothelial cells, thymocytes, regulatory T cells, a subset of T follicular helper cells, neurons, and diverse human solid tumors (PMID: 31944572; 14991591; 18704117). Neuropilin 1 is involved in immunity, cardiovascular development, neuronal guidance, cell migration, angiogenesis and cancer pathogenesis (PMID: 24263240).