Napsin A Monoclonal antibody, PBS Only

Napsin A Monoclonal Antibody for IHC, IF/ICC, FC (Intra), ELISA
Cat No. 60259-2-PBS
Clone No.1H7F2

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

IHC, IF/ICC, FC (Intra), ELISA

NAPSA, KAP, EC:3.4.23.-, Aspartyl protease 4, ASP4

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

60259-2-PBS targets Napsin A in IHC, IF/ICC, FC (Intra), ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen Napsin A fusion protein Ag9721 Predict reactive species
Full Name napsin A aspartic peptidase
Calculated Molecular Weight 420 aa, 45 kDa
GenBank Accession NumberBC017842
Gene Symbol Napsin A
Gene ID (NCBI) 9476
RRIDAB_2881381
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDO96009
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Napsin is found in two isoforms, napsin A and B, with highly homologous nucleotide sequences (91.2%). Napsin A appears to be a functional proteinase, predominantly expressed in lung and kidney. Napsin B is transcribed exclusively in cells related to the immune system and lacks an in-frame stop codon and is believed to be a pseudogene.(PMID:12698189). Napsin A is superior to TTF-1 in distinguishing primary lung ACA from other carcinomas (except kidney), particularly primary lung small cell carcinoma, and primary thyroid carcinoma.(PMID:22288963).

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