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NTRK1 Monoclonal antibody, PBS Only

NTRK1 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3B11C7

Cat no : 60548-1-PBS

Synonyms

TRK1, Trk A, TRK, p140 TrkA, MTC

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using NTRK1 Monoclonal antibody (60548-1-Ig)

    WB analysis using 60548-1-Ig (same clone as 60548-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 60548-1-Ig (NTRK1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60548-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of NK-92 cells using NTRK1 Monoclonal antibody (60548-1-Ig)

    WB analysis of NK-92 using 60548-1-Ig (same clone as 60548-1-PBS)

    NK-92 cells were subjected to SDS PAGE followed by western blot with 60548-1-Ig (NTRK1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60548-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using NTRK1 Monoclonal antibody (60548-1-Ig)

    WB analysis using 60548-1-Ig (same clone as 60548-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 60548-1-Ig (NTRK1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60548-1-PBS in a different storage buffer formulation.

Product Information

60548-1-PBS targets NTRK1 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen NTRK1 fusion protein Ag27985
Full Name neurotrophic tyrosine kinase, receptor, type 1
Calculated Molecular Weight 88 kDa
Observed Molecular Weight140 kDa
GenBank Accession NumberNM_001007792
Gene Symbol NTRK1
Gene ID (NCBI) 4914
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

NTRK1(Neurotrophic tyrosine kinase receptor 1) is located on chromosome 1q23.1 and is responsible for a rare genetic disorder, CIPA (congenital insensitivity to pain with anhidrosis) (PMID: 37907480). As a neurotrophin receptor, NTRK1 is abundantly expressed in human neuronal tissues and plays an integral role in the development and function of the human nervous system (PMID: 27843590). NTRK1 also regulates the survival and proliferation of cholinergic neurons (PMID: 20054812).