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NTB-A/SLAMF6 Recombinant antibody, PBS Only

NTB-A/SLAMF6 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241384G5

Cat no : 84211-4-PBS

Synonyms

SLAMF6, Ly108, KALIb, KALI, CD352

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using NTB-A/SLAMF6 Recombinant antibody (84211-4-RR)

    WB analysis using 84211-4-RR (same clone as 84211-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84211-4-RR (NTB-A/SLAMF6 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84211-4-PBS in a different storage buffer formulation.

Product Information

The immunogen of 84211-4-PBS is NTB-A/SLAMF6 Fusion Protein expressed in E. coli.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Fusion Protein
Full Name SLAM family member 6
Calculated Molecular Weight37kDa
Observed Molecular Weight60 kDa
GenBank Accession NumberNM_001184714.2
Gene Symbol SLAMF6
Gene ID (NCBI) 114836
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Signaling lymphocyte activation molecule 6 (SLAMF6) (Ly108 in mice, NTB-A or SF2000 in humans) is a homophilic receptor belonging to the superfamily immunoglobulin (Ig) domain-containing molecules (PMID:31199820). SLAMF6 is a type I transmembrane protein with two extracellular immunoglobins (Ig)-like domains and three cytoplasmic tyrosine-based signaling motifs, one of which is immunoreceptor tyrosine-based switch motif (PMID:31315913). SLAMF6 is expressed on a wide variety of immune cells including T cells (also TFH), B cells, NK cells (expressed in humans only), double positive thymocytes, eosinophils, and neutrophils (mouse only) (PMID:11862385).