NSUN2 Recombinant antibody, PBS Only
NSUN2 Uni-rAbTM Recombinant Antibody for WB, IF/ICC, FC (Intra), Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
WB, IF/ICC, FC (Intra), Indirect ELISA
Conjugate
Unconjugated
CloneNo.
230186H8
Cat no : 82894-7-PBS
Synonyms
Validation Data Gallery
Product Information
82894-7-PBS targets NSUN2 in WB, IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | NSUN2 fusion protein Ag14791 |
Full Name | NOL1/NOP2/Sun domain family, member 2 |
Calculated Molecular Weight | 767 aa, 86 kDa |
Observed Molecular Weight | 90-100 kDa |
GenBank Accession Number | BC001041 |
Gene Symbol | NSUN2 |
Gene ID (NCBI) | 54888 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
NSUN2, also known as SAKI or Misu (Myc-induced SUN-domain-containing protein), is a methyltransferase which catalyses (cytosine-5-)-methylation of tRNA. NSUN2 is direct target gene of c-Myc and may act downstream of Myc to regulate epidermal cell growth and proliferation. NSUN2 is overexpressed in various cancer tissues and may be a valuable target for cancer therapy and a cancer diagnostic marker. Recently a splicing mutation in NSUN2 has been identified as the cause of a Dubowitz-like syndrome, an autosomal recessive disorder.