NQO1 Monoclonal antibody, PBS Only

NQO1 Monoclonal Antibody for Indirect ELISA, IHC, WB
Cat No. 67240-1-PBS
Clone No.1E5G7

Host / Isotype

Mouse / IgG2a

Reactivity

rat, human

Applications

Indirect ELISA, IHC, WB

DT diaphorase, DIA4, DIA 4, DHQU, Azoreductase

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

67240-1-PBS targets NQO1 in Indirect ELISA, IHC, WB applications and shows reactivity with rat, human samples.

Tested Reactivity rat, human
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen NQO1 fusion protein Ag28933 Predict reactive species
Full Name NAD(P)H dehydrogenase, quinone 1
Calculated Molecular Weight 274 aa, 31 kDa
Observed Molecular Weight 29-31 kDa
GenBank Accession NumberBC007659
Gene Symbol NQO1
Gene ID (NCBI) 1728
RRIDAB_2882519
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP15559
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

NQO1, also named as DIA4, NMOR1, DTD and QR1, belongs to the NAD(P)H dehydrogenase (quinone) family. This enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. It is known to be involved in benzene metabolism. In human studies of ozone exposure, polymorphisms in oxidative stress genes (NQO1, GSTM1, GSTP1) modify respiratory symptoms, lung function, biomarkers and risk of asthma. (PMID:18511640; 18848868 )

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