Mouse MYD88 Polyclonal antibody, PBS Only

MYD88 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 29946-1-PBS

Synonyms

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Validation Data Gallery

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  WB analysis using 29946-1-AP (same clone as 29946-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29946-1-AP (MYD88 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29946-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse liver using 29946-1-AP (same clone as 29946-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 29946-1-AP (MYD88 antibody) at dilution of 1:800 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29946-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse liver using 29946-1-AP (same clone as 29946-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 29946-1-AP (MYD88 antibody) at dilution of 1:800 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29946-1-PBS in a different storage buffer formulation.

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Product Information

29946-1-PBS targets MYD88 in WB, IHC, Indirect ELISA applications and shows reactivity with mouse, rat samples.

• Tested Reactivity: mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: MYD88 fusion protein Ag30662
• Full Name: myeloid differentiation primary response gene 88
• Calculated Molecular Weight: 34 kDa
• Observed Molecular Weight: 29-34 kDa
• GenBank Accession Number: NM_010851
• Gene Symbol: Myd88
• Gene ID (NCBI): 17874
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

MYD88 is a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. MYD88 is the key adaptor protein for the interleukin-1 receptor (IL-1R) and most Toll-like receptors (TLRs), which are essential for innate immunity and pathogen-associated molecular pattern recognition. Mutations in the MyD88 gene lead to the development of cancer in humans and mice suggesting that MyD88 also plays a cell autonomous role in tissue homeostasis. MYD88 is detected in bone marrow.