Product Information
67608-1-PBS targets MYBPC3 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with Human, mouse, rat, pig, rabbit samples.
Tested Reactivity | Human, mouse, rat, pig, rabbit |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | MYBPC3 fusion protein Ag15848 Predict reactive species |
Full Name | myosin binding protein C, cardiac |
Calculated Molecular Weight | 1274 aa, 141 kDa |
Observed Molecular Weight | 140-150 kDa |
GenBank Accession Number | BC151211 |
Gene Symbol | MYBPC3 |
Gene ID (NCBI) | 4607 |
RRID | AB_2882814 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q14896 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
MYBPC3 belongs to the immunoglobulin superfamily and MyBP family. MYBPC3 located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Defects in MYBPC3 are the cause of cardiomyopathy familial hypertrophic type 4 (CMH4).