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MVK Monoclonal antibody, PBS Only

MVK Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2F1D3

Cat no : 67820-1-PBS

Synonyms

FLJ96772, LRBP, mevalonate kinase, MK, MVK, MVLK

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using MVK Monoclonal antibody (67820-1-Ig)

    WB analysis using 67820-1-Ig (same clone as 67820-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67820-1-Ig (MVK antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67820-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of U2OS cells using MVK Monoclonal antibody (67820-1-Ig)

    WB analysis of U2OS using 67820-1-Ig (same clone as 67820-1-PBS)

    U2OS cells were subjected to SDS PAGE followed by western blot with 67820-1-Ig (MVK antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67820-1-PBS in a different storage buffer formulation.

Product Information

67820-1-PBS targets MVK in WB, Indirect ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen MVK fusion protein Ag28887
Full Name mevalonate kinase
Calculated Molecular Weight 396 aa, 42 kDa
Observed Molecular Weight 42 kDa
GenBank Accession NumberBC016140
Gene Symbol MVK
Gene ID (NCBI) 4598
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

MVK (Mevalonate kinase) is a 42 kDa cytoplasmic protein that belongs to the GHMP kinase family. Mevalonate kinase catalyzes the ATP-dependent phosphorylation of mevalonic acid to form mevalonate 5-phosphate. Defects in mevalonate kinase can cause mevalonic aciduria (MEVA). It is an accumulation of mevalonic acid which causes a variety of symptoms such as psychomotor retardation, dysmorphic features, cataracts, hepatosplenomegaly, lymphadenopathy, anemia, hypotonia, myopathy and ataxia.