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  • Featured Product
  • KD/KO Validated

MTX1 Polyclonal antibody, PBS Only

MTX1 Polyclonal Antibody for WB, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 15529-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using MTX1 Polyclonal antibody (15529-1-AP)

    WB analysis using 15529-1-AP (same clone as 15529-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 15529-1-AP (MTX1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15529-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using MTX1 Polyclonal antibody (15529-1-AP)

    WB analysis using 15529-1-AP (same clone as 15529-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 15529-1-AP (MTX1 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15529-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of MCF-7 cells using MTX1 Polyclonal antibody (15529-1-AP)

    IP experiment of MCF-7 using 15529-1-AP (same clone as 15529-1-PBS)

    IP result of anti-MTX1 (IP:15529-1-AP, 4ug; Detection:15529-1-AP 1:700) with MCF-7 cells lysate 1280ug. This data was developed using the same antibody clone with 15529-1-PBS in a different storage buffer formulation.

Product Information

15529-1-PBS targets MTX1 in WB, IP, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen MTX1 fusion protein Ag7685
Full Name metaxin 1
Calculated Molecular Weight 51 kDa
Observed Molecular Weight 35 kDa
GenBank Accession NumberBC001906
Gene Symbol MTX1
Gene ID (NCBI) 4580
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

METAXINs are proteins located in the outer membrane of the mammalian mitochondrion. METAXIN 1 was characterized firstly and was found to play a role in the import of mitochondrial precursor proteins. It may also play a role in the assembly of b-barrel proteins into the outer membrane METAXIN1 was reported to be essential for survival of the postimplantation mouse embryo. METAXIN 1 has multiple transcripts. Several isoforms of METAXIN 1 exist due to the alternative splicing, with the predicted MW of 51, 48 and 36 kDa, respectively. Metaxin 1 interacts with metaxin 2, a novel related protein associated with the mammalian mitochondrial outer membrane and form complex in the mitochondrion outer membrane.