Product Information
66172-2-PBS targets MSH6 as part of a matched antibody pair:
MP50291-1: 66172-2-PBS capture and 66172-3-PBS detection (validated in Cytometric bead array)
MP50291-2: 66172-2-PBS capture and 66172-4-PBS detection (validated in Cytometric bead array)
Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
| Tested Reactivity | human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | MSH6 fusion protein Ag12645 Predict reactive species |
| Full Name | mutS homolog 6 (E. coli) |
| Calculated Molecular Weight | 153 kDa |
| Observed Molecular Weight | 150-160 kDa |
| GenBank Accession Number | BC004246 |
| Gene Symbol | MSH6 |
| Gene ID (NCBI) | 2956 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | P52701 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
MSH6, also named as DNA mismatch repair protein Msh6 or GTMBP, is a 1360 amino acid protein, which contains one PWWP domain and belongs to the DNA mismatch repair MutS family. MSH6 localizes in the nucleus and is a component of the post-replicative DNA mismatch repair system. Msh2 and Msh6 form a protein complex required to repair mismatches generated during DNA replication.
