• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

MRP1 Monoclonal antibody, PBS Only

MRP1 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

1G4A2

Cat no : 67228-1-PBS

Synonyms

ABC29, ABCC, ABCC1, Leukotriene C(4) transporter, LTC4 transporter, MRP, MRP1

Validation Data Gallery

Filter:
  • Western Blot (WB) analysis of various lysates using MRP1 Monoclonal antibody (67228-1-Ig)

    WB analysis using 67228-1-Ig (same clone as 67228-1-PBS)

    Non-boil and boiled HepG2 and A549 cell lysates were subjected to SDS PAGE followed by western blot with 67228-1-Ig (ABCC1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. Left panel was exposed for 20 sec. and right panel was exposed for 1 min. This data was developed using the same antibody clone with 67228-1-PBS in a different storage buffer formulation.

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

67228-1-PBS targets MRP1 in WB, ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen MRP1 fusion protein Ag27048
Full Name ATP-binding cassette, sub-family C (CFTR/MRP), member 1
Calculated Molecular Weight 172 kDa
Observed Molecular Weight 180-190 kDa
GenBank Accession NumberNM_004996
Gene Symbol ABCC1
Gene ID (NCBI) 4363
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS only
Storage ConditionsStore at -20°C. Stable for one year after shipment.

Background Information

Multidrug resistant-associated protein 1 (MRP1; ABCC1) is a member of the ATP-binding cassette (ABC) transporter protein superfamily, subfamily C. MRP1 is overexpressed in cancers and contributes to the occurrence of multidrug resistance (MDR). Expression of MRP1 has been considered as a negative marker for the outcome of chemotherapy. Recently MRP1 has been reported to play a crucial role in Aβ clearance at the blood-brain barrier.