MRGPRD Polyclonal antibody, PBS Only

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  IHC staining of mouse small intestine using 23640-1-AP (same clone as 23640-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse small intestine tissue slide using 23640-1-AP (MRGPRD antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23640-1-PBS in a different storage buffer formulation.

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  IHC staining of rat dorsal root ganglion using 23640-1-AP (same clone as 23640-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat dorsal root ganglion tissue slide using 23640-1-AP (MRGPRD antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23640-1-PBS in a different storage buffer formulation.

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  IF Staining of mouse small intestine using 23640-1-AP (same clone as 23640-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse small intestine tissue using MRGPRD antibody (23640-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23640-1-PBS in a different storage buffer formulation.

• 

  IF Staining of mouse small intestine using 23640-1-AP (same clone as 23640-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse small intestine tissue using MRGPRD antibody (23640-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23640-1-PBS in a different storage buffer formulation.

MRGPRD Polyclonal Antibody for IHC, IF-P, Indirect ELISA

Cat No. 23640-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IHC, IF-P, Indirect ELISA

Synonyms

MRGD, Mas-related G-protein coupled receptor member D, MAS related GPR, member D, G-protein coupled receptor TGR7, Beta-alanine receptor

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Product Information

23640-1-PBS targets MRGPRD in IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: MRGPRD fusion protein Ag20316
• Full Name: MAS-related GPR, member D
• Calculated Molecular Weight: 321 aa, 36 kDa
• GenBank Accession Number: BC156660
• Gene Symbol: MRGPRD
• Gene ID (NCBI): 116512
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen Affinity purified
• UNIPROT ID: Q8TDS7
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

MRGPRD (MAS-related G-protein coupled receptor, D), also referred to as hGPCR45 or TGR7, was identified as a novel GPCR in murine and human genomes. As for MRGD, its expression was found in dorsal root ganglia (DRG) and co-localized with Vanilloid receptor-1 (VR-1), which is an essential receptor for heat and pain sensation (PMID: 22715397).