Product Information
83856-5-PBS targets MIOS in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | MIOS fusion protein Ag15148 Predict reactive species |
Full Name | missing oocyte, meiosis regulator, homolog (Drosophila) |
Calculated Molecular Weight | 875 aa, 99 kDa |
Observed Molecular Weight | 82 kDa |
GenBank Accession Number | BC005883 |
Gene Symbol | MIOS |
Gene ID (NCBI) | 54468 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | Q9NXC5 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
The mechanistic target of rapamycin complex 1 (mTORC1) controls growth by regulating anabolic and catabolic processes in response to environmental cues, including nutrients. Amino acids signal to mTORC1 through the Rag GTPases, which are regulated by several protein complexes, including GATOR1 and GATOR2. GATOR2, which has five components (WDR24, MIOS, WDR59, SEH1L, SEC13), is required for amino acids to activate mTORC1. PMID: 35831510