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  • Featured Product
  • KD/KO Validated

MGAT4C Polyclonal antibody, PBS Only

MGAT4C Polyclonal Antibody for WB, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 17841-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using MGAT4C Polyclonal antibody (17841-1-AP)

    WB analysis using 17841-1-AP (same clone as 17841-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17841-1-AP (MGAT4C antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17841-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of mouse testis tissue using MGAT4C Polyclonal antibody (17841-1-AP)

    IP experiment of mouse testis using 17841-1-AP (same clone as 17841-1-PBS)

    IP result of anti-MGAT4C (IP:17841-1-AP, 4ug; Detection:17841-1-AP 1:400) with mouse testis tissue lysate 4000ug. This data was developed using the same antibody clone with 17841-1-PBS in a different storage buffer formulation.

Product Information

17841-1-PBS targets MGAT4C in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen MGAT4C fusion protein Ag12201
Full Name mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
Calculated Molecular Weight 478 aa, 56 kDa
Observed Molecular Weight 55 kDa
GenBank Accession NumberBC064141
Gene Symbol MGAT4C
Gene ID (NCBI) 25834
RRIDAB_2143048
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

MGAT4C is predicted to be a glycosyltransferase that catalyzes a GlcNAc β1-4 linkage to the core mannose residues of N-glycans, resulting in N-glycans with tri- or tetraantennary structures.Recently MGAT4C has been found to get involved in processing complex N-glycan structures on CD133 and CD133 has been identified as a substrate of MGAT4C. Given to the fact that CD133 is widely used as a marker of numerous stem cell and cancer stem cell types, MGAT4C may have an important role in certain cancers. (PMID: 21937449)