MAP2 Recombinant antibody, PBS Only
MAP2 Uni-rAbTM Recombinant Antibody for IF/ICC, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
IF/ICC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
241653H8
Cat no : 84306-4-PBS
Synonyms
Validation Data Gallery
Product Information
The immunogen of 84306-4-PBS is MAP2 Fusion Protein expressed in E. coli.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | MAP2 fusion protein Ag11580 |
Full Name | microtubule-associated protein 2 |
Calculated Molecular Weight | 200 kDa |
GenBank Accession Number | BC038857 |
Gene Symbol | MAP2 |
Gene ID (NCBI) | 4133 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
MAP2 (microtubule-associated protein 2) is a cytoskeleton protein abundant in the brain and has an important role in neuronal morphogenesis. Multiple high MW and low MW MAP2 isoforms are expressed within the proximal segment of axons, dendrites, and cell bodies. The expression of MAP2 is regulated in both a tissue- and developmentally-specific manner. The 280 kDa MAP2B is present throughout rat brain development, and the slightly larger MAP2A appears first during the end of the second week of postnatal life. MAP2C, composed of several bands of about 70 kDa, is present during early brain development and largely disappears from the mature brain except for the retina, olfactory bulb, and cerebellum. In addition, some isoforms with lower MW around 50-60 kDa also exist.