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LINGO1 Polyclonal antibody, PBS Only

LINGO1 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 19097-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of mouse brain tissue using LINGO1 Polyclonal antibody (19097-1-AP)

    WB analysis of mouse brain using 19097-1-AP (same clone as 19097-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 19097-1-AP (LINGO1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19097-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of mouse brain tissue using LINGO1 Polyclonal antibody (19097-1-AP)

    WB analysis of mouse brain using 19097-1-AP (same clone as 19097-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 19097-1-AP (LINGO1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19097-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of rat brain tissue using LINGO1 Polyclonal antibody (19097-1-AP)

    WB analysis of rat brain using 19097-1-AP (same clone as 19097-1-PBS)

    rat brain tissue were subjected to SDS PAGE followed by western blot with 19097-1-AP (LINGO1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19097-1-PBS in a different storage buffer formulation.

Product Information

19097-1-PBS targets LINGO1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen LINGO1 fusion protein Ag13553
Full Name leucine rich repeat and Ig domain containing 1
Calculated Molecular Weight 70 kDa
Observed Molecular Weight 83 kDa
GenBank Accession NumberBC011057
Gene Symbol LINGO1
Gene ID (NCBI) 84894
RRIDAB_10638484
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

LINGO-1 is a transmembrane receptor that contains 12 leucine-rich repeats and an immunoglobulin domain. It is expressed primarily in the central nervous system. LINGO-1 binds Nogo-66 receptor (NgR) and p75 and that is a functional component of the NgR/p75 signaling complex (PMID: 14966521). This protein has a calculated molecular weight of 70 kDa and migrates at higher molecular weight due to glycosylation (PMID: 21872576; 25257685; 18326721).