LINGO1 Polyclonal antibody, PBS Only
LINGO1 Polyclonal Antibody for WB, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
Cat no : 19097-1-PBS
Synonyms
Validation Data Gallery
Product Information
19097-1-PBS targets LINGO1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | LINGO1 fusion protein Ag13553 |
Full Name | leucine rich repeat and Ig domain containing 1 |
Calculated Molecular Weight | 70 kDa |
Observed Molecular Weight | 83 kDa |
GenBank Accession Number | BC011057 |
Gene Symbol | LINGO1 |
Gene ID (NCBI) | 84894 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
LINGO-1 is a transmembrane receptor that contains 12 leucine-rich repeats and an immunoglobulin domain. It is expressed primarily in the central nervous system. LINGO-1 binds Nogo-66 receptor (NgR) and p75 and that is a functional component of the NgR/p75 signaling complex (PMID: 14966521). This protein has a calculated molecular weight of 70 kDa and migrates at higher molecular weight due to glycosylation (PMID: 21872576; 25257685; 18326721).