- Featured Product
- KD/KO Validated
LETM1 Monoclonal antibody, PBS Only
LETM1 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human, rat
Applications
WB, IF/ICC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
2B9B9
Cat no : 68208-1-PBS
Synonyms
Validation Data Gallery
Product Information
68208-1-PBS targets LETM1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with Human, rat samples.
Tested Reactivity | Human, rat |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | LETM1 fusion protein Ag8851 |
Full Name | leucine zipper-EF-hand containing transmembrane protein 1 |
Calculated Molecular Weight | 739 aa, 83 kDa |
Observed Molecular Weight | 83 kDa |
GenBank Accession Number | BC021208 |
Gene Symbol | LETM1 |
Gene ID (NCBI) | 3954 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
LETM1 is a mitochondrial inner membrane protein. It functions to maintain the mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. It served as an anchor protein for complex formation between mitochondria and ribosome, and regulated mitochondrial biogenesis. It was also identified inWolf-Hirschhorn syndrome, and was deleted in nearly all patients with the syndrome. A recent study determined that adenovirus-mediated LETM1 may provide a useful target for designing lung tumor prevention and treatment.