LBR Polyclonal antibody

LBR Polyclonal Antibody for FC, IF, IP, WB, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 12398-1-AP


DHCR14B, lamin B receptor, LBR, LMN2R, PHA

Tested Applications

Positive WB detected inA375 cells, human brain tissue, C2C12 cells
Positive IP detected inA375 cells
Positive IF detected inHela cells, C6 cells, HepG2 cells
Positive FC detected inJurkat cells
Planning an IF experiment? We recommend our CoraLite®488, CoraLite®555 and CoraLite®650 conjugated versions of this antibody.

Recommended dilution

Western Blot (WB)WB : 1:1000-1:4000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
Immunofluorescence (IF)IF : 1:25-1:100
Sample-dependent, check data in validation data gallery

Product Information

12398-1-AP targets LBR in WB, IP, IF, FC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen LBR fusion protein Ag3088
Full Name lamin B receptor
Calculated molecular weight 615 aa, 71 kDa
Observed molecular weight 58 kDa
GenBank accession numberBC020079
Gene symbol LBR
Gene ID (NCBI) 3930
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Lamin-B receptor (LBR) belongs to the ERG4/ERG24 family. LBR is a 58-kDa integral protein of the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the inner nuclear membrane. LBR may mediate the interaction between chromatin and lamin B. Mutations of the LBR gene have been associated with autosomal recessive HEM/Greenberg skeletal dysplasia.


Product Specific Protocols
WB protocol for LBR antibody 12398-1-APDownload protocol
IF protocol for LBR antibody 12398-1-APDownload protocol
IP protocol for LBR antibody 12398-1-APDownload protocol
FC protocol for LBR antibody 12398-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



JCI Insight

A common pathomechanism in GMAP-210- and LBR-related diseases.

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