KAT2A/GCN5 Polyclonal antibody, PBS Only

KAT2A/GCN5 Polyclonal Antibody for IF/ICC, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 28390-1-PBS

Synonyms

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Validation Data Gallery

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  IP experiment of hTERT-RPE1 using 28390-1-AP (same clone as 28390-1-PBS)

  IP result of anti-KAT2A (IP:28390-1-AP, 4ug; Detection:28390-1-AP 1:400) with hTERT-RPE1 cells lysate 1645 ug. This data was developed using the same antibody clone with 28390-1-PBS in a different storage buffer formulation.

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  IP experiment of LNCaP using 28390-1-AP (same clone as 28390-1-PBS)

  IP result of anti-KAT2A/GCN5 (IP:28390-1-AP, 4ug; Detection:28390-1-AP 1:6000) with LNCaP cells lysate 1200 ug. This data was developed using the same antibody clone with 28390-1-PBS in a different storage buffer formulation.

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  IF Staining of HeLa using 28390-1-AP (same clone as 28390-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed HeLa cells using KAT2A/GCN5 antibody (28390-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 28390-1-PBS in a different storage buffer formulation.

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Product Information

28390-1-PBS targets KAT2A/GCN5 in IF/ICC, IP, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: KAT2A/GCN5 fusion protein Ag29005
• Full Name: K(lysine) acetyltransferase 2A
• Calculated Molecular Weight: 94 kDa
• Observed Molecular Weight: 94 kDa
• GenBank Accession Number: BC032743
• Gene Symbol: KAT2A
• Gene ID (NCBI): 2648
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

GCN5, encoded by KAT2A, is a member of nuclear A-type histone acetyltransferase (HAT) which has direct impact on gene transcription. Additionally, GCN5 has roles in cell cycle regulation, DNA replication, and DNA repair, highlighting it as key player in the maintenance of genome stability. GCN5 is a coactivator of c-MYC oncogene protein and has oncogenic roles in various cancers.