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  • Featured Product
  • KD/KO Validated

Jagged1 Monoclonal antibody, PBS Only

Jagged1 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgA

Reactivity

Human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

2A7D11

Cat no : 66890-1-PBS

Synonyms

AGS, AHD, AWS, CD339, HJ1, JAG1, jagged 1 (Alagille syndrome), Jagged1, JAGL1, Protein jagged 1

Validation Data Gallery

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  • Western Blot (WB) analysis of HEK-293 cells using Jagged1 Monoclonal antibody (66890-1-Ig)

    WB analysis of HEK-293 using 66890-1-Ig (same clone as 66890-1-PBS)

    WB result of Jagged1 antibody (66890-1-Ig; 1:12000; incubated at room temperature for 1.5 hours) with sh-Control and sh-Jagged1 transfected HEK-293 cells. This data was developed using the same antibody clone with 66890-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HT-29 cells using Jagged1 Monoclonal antibody (66890-1-Ig)

    WB analysis of HT-29 using 66890-1-Ig (same clone as 66890-1-PBS)

    HT-29 cells were subjected to SDS PAGE followed by western blot with 66890-1-Ig (Jagged1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66890-1-PBS in a different storage buffer formulation.

Product Information

66890-1-PBS targets Jagged1 in WB, ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgA
Class Monoclonal
Type Antibody
Immunogen Jagged1 fusion protein Ag11891
Full Name jagged 1 (Alagille syndrome)
Calculated Molecular Weight 1218 aa, 134 kDa
Observed Molecular Weight 150 kDa
GenBank Accession NumberBC098393
Gene Symbol Jagged1
Gene ID (NCBI) 182
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS only
Storage ConditionsStore at -80°C.

Background Information

Jagged1 is a type I, membrane- anchored, multidomain protein and a ligand of the Notch receptor. The receptor-ligand interaction can trigger the Notch signaling and activate transcription factors that play key roles in cell differentiation and morphogenesis. The predicted MW of Jagged1 is 134 kDa, while higher MW around 150-180 kDa had been observed in literations (PMID: 9716576, 9596653).