IQUB Recombinant antibody, PBS Only

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  IHC staining of mouse testis using 83847-5-RR (same clone as 83847-5-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 83847-5-RR (IQUB antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83847-5-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse testis using 83847-5-RR (same clone as 83847-5-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 83847-5-RR (IQUB antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83847-5-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83847-5-RR

  Biolayer interferometry (BLl) kinetic assays of 83847-5-RR against Human IQUB were performed. The affinity constant is 0.144 nM.

IQUB {ptg:Brand} Recombinant Antibody for IHC, ELISA

Cat No. 83847-5-PBS

Clone No.240957A11

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, ELISA

Synonyms

IQ motif and ubiquitin-like domain-containing protein, 240957A11

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Product Information

83847-5-PBS targets IQUB in IHC, ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: IQUB fusion protein Ag19507
• Full Name: IQ motif and ubiquitin domain containing
• Calculated Molecular Weight: 791 aa, 93 kDa
• Observed Molecular Weight: 70 kDa
• GenBank Accession Number: BC128181
• Gene Symbol: IQUB
• Gene ID (NCBI): 154865
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: Q8NA54
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

IQUB (IQ motif and ubiquitin domain containing) was discovered in 2002,4 which was located on chromosome 7q31.32 and its encoded protein mainly contained 2 domains, ubiquitin-like domain and IQ domain. IQUB had apparently higher expression in breast cancer than that in normal tissues, suggesting that it may act an important role in the occurrence and development of breast cancer (PMID: 29968965). IQUB is a critical RS1 adaptor in mouse sperm flagella, and is critical for sperm motility and fertilization (PMID: 36417862).