Anti-Human IL-4RA/CD124 Rabbit Recombinant Antibody

IL-4RA/CD124 Recombinant Antibody for FC
Cat No. 98203-1-RR
Clone No.241824D8

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

IL4R, IL 4R subunit alpha, IL 4R alpha, IL 4 receptor subunit alpha, IL 4 binding protein

Formulation:  PBS and Azide
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Tested Applications

Positive FC detected inhuman PBMCs

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

98203-1-RR targets IL-4RA/CD124 in FC applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Recombinant protein Predict reactive species
Full Name interleukin 4 receptor
Calculated Molecular Weight90 kDa
GenBank Accession NumberNM_000418.4
Gene Symbol IL-4R
Gene ID (NCBI) 3566
RRIDAB_3672335
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP24394-1
Storage Buffer PBS with 0.09% sodium azide, pH 7.3.
Storage ConditionsStore at 2 - 8°C. Stable for one year after shipment.

Background Information

IL-4 receptor alpha chain (IL-4RA), also known as CD124, is a transmembrane glycoprotein expressed on a wide variety of hematopoietic and non-hematopoietic cells. It is a receptor for both IL-4 and IL-13. IL-4RA can complex with the common gamma chain (IL-2R gamma or CD132) and utilizes JAK1 and JAK2 for signal transduction, while complexes of IL-4RA with IL-13RA1 subunit mediate signals via JAK2 and Tyk2. The IL-4 response is involved in promoting Th2 differentiation. The IL-4/IL-13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation.

Protocols

Product Specific Protocols
FC protocol for IL-4RA/CD124 antibody 98203-1-RRDownload protocol
Standard Protocols
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