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IL-18 Monoclonal antibody, PBS Only

IL-18 Monoclonal Antibody for WB, IHC, IF-P, FC (Intra), ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human

Applications

WB, IHC, IF-P, FC (Intra), ELISA

Conjugate

Unconjugated

CloneNo.

5C6F8

Cat no : 60070-1-PBS

Synonyms

IL18, Pre-IL18, IL-1 gamma, IL 18, IL 1 gamma



Product Information

60070-1-PBS targets IL-18 in WB, IHC, IF-P, FC (Intra), ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen IL-18 fusion protein Ag1063
Full Name IL-18
Calculated Molecular Weight 193 aa, 22 kDa
Observed Molecular Weight 24 kDa
GenBank Accession NumberBC007461
Gene Symbol IL-18
Gene ID (NCBI) 3606
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

IL18, is a proinflammatory cytokine involved in the development of Th1 cells and in immune response. It can stimulate the NK cells and certain T cells to release IFN gamma which plays an important role in activating the macrophages or other cells. IL18 has been demonstrated to have the potential to enhance Fas ligand-mediated cytotoxicity, which is increased in PE and regulates placental apoptosis. IL18 is synthesized as a 24 kDa precursor and then cleaved into a biologically activate 18 kDa form.