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- KD/KO Validated
IL-18 Monoclonal antibody, PBS Only
IL-18 Monoclonal Antibody for WB, IHC, IF-P, FC (Intra), ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
human
Applications
WB, IHC, IF-P, FC (Intra), ELISA
Conjugate
Unconjugated
CloneNo.
5C6F8
Cat no : 60070-1-PBS
Synonyms
Validation Data Gallery
Product Information
60070-1-PBS targets IL-18 in WB, IHC, IF-P, FC (Intra), ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | IL-18 fusion protein Ag1063 |
Full Name | IL-18 |
Calculated Molecular Weight | 193 aa, 22 kDa |
Observed Molecular Weight | 24 kDa |
GenBank Accession Number | BC007461 |
Gene Symbol | IL-18 |
Gene ID (NCBI) | 3606 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
IL18, is a proinflammatory cytokine involved in the development of Th1 cells and in immune response. It can stimulate the NK cells and certain T cells to release IFN gamma which plays an important role in activating the macrophages or other cells. IL18 has been demonstrated to have the potential to enhance Fas ligand-mediated cytotoxicity, which is increased in PE and regulates placental apoptosis. IL18 is synthesized as a 24 kDa precursor and then cleaved into a biologically activate 18 kDa form.