Anti-Rat IL-1 beta Rabbit Recombinant Antibody, PBS Only

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  FC experiment of Transfected HEK-293T using 98310-2-RR (same clone as 98310-2-PBS)

  1x10^6 HEK-293T cells or IL-1 beta transfected HEK-293T cells were intracellularly stained with 0.25 ug Anti-Rat Il1 beta Rabbit RecAb (98310-2-RR, Clone: 241001F11) and Multi-rAb CoraLite ® Plus 647-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR005). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98310-2-PBS in a different storage buffer formulation.

• 

  FC experiment of Transfected HEK-293T using 98310-2-RR (same clone as 98310-2-PBS)

  1x10^6 HEK-293T cells or IL-1 beta transfected HEK-293T cells were intracellularly stained with 0.25 ug Anti-Rat Il1 beta Rabbit RecAb (98310-2-RR, Clone: 241001F11) and Multi-rAb CoraLite ® Plus 647-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR005) (red), or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98310-2-PBS in a different storage buffer formulation.

IL-1 beta Uni-rAb^TM Recombinant Antibody for FC (Intra)

Cat No. 98310-2-PBS

Clone No.241001F11

Host / Isotype

Rabbit / IgG

Reactivity

rat

Applications

FC (Intra)

Synonyms

Il1 beta, Il1b, IL 1 beta, IL-1 beta,IL 1 beta,IL1beta, IL-1 β

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Product Information

98310-2-PBS targets IL-1 beta in FC (Intra) applications and shows reactivity with rat samples.

• Tested Reactivity: rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant protein
• Full Name: interleukin 1 beta
• Calculated Molecular Weight: 31 kDa
• GenBank Accession Number: NM_031512
• Gene Symbol: IL-1 beta
• Gene ID (NCBI): 24494
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q63264
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Interleukin-1, produced mainly by blood monocytes, mediates the panoply of host reactions collectively known as acute phase response. It is identical to endogenous pyrogen. The multiple biologic activities that define IL1 are properties of a 15- to 18-kD protein that is derived from a 30- to 35-kD precursor. Interleukin 1β (IL-1B) is a member of the interleukin 1 cytokine family. It is a pro-inflammatory cytokine against infection, playing an important role in the pathogenesis of cancers. It signals through various adaptor proteins and kinases that lead to activation of numerous downstream targets.