IGFBP4 Polyclonal antibody, PBS Only

• 

  WB analysis using 30952-1-AP (same clone as 30952-1-PBS)

  MDA-MB-231 cells lysates were subjected to SDS PAGE followed by western blot with 30952-1-AP (IGFBP4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30952-1-PBS in a different storage buffer formulation.

IGFBP4 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 30952-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

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Product Information

30952-1-PBS targets IGFBP4 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Recombinant protein

• Full Name: insulin-like growth factor binding protein 4
• Calculated Molecular Weight: 28 kDa
• Observed Molecular Weight: 28-40 kDa
• GenBank Accession Number: NM_001552.3
• Gene Symbol: IGFBP4
• Gene ID (NCBI): 3487
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P22692-1
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

IGFBP4, also named as IBP4, is a 258 amino acid protein, which contains one IGFBP N-terminal domain and one thyroglobulin type-1 domain. IGFBP4 is the smallest member of the insulin-like growth factor binding protein family (IGFBP). It is a hepatic protein that plays a role in modulating the activity and bioavailability of IGF-I. The expression of IGFBP4 was found to increase under conditions of hypoxia. IGFBP4 is highly expressed in adipocytes and osteoblasts and is inhibitory of IGFs in vitro. (PMID: 28938423, PMID: 34646401).