IGFALS Polyclonal antibody, PBS Only

• 

  WB analysis of human plasma using 24545-1-AP (same clone as 24545-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 24545-1-AP (IGFALS antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24545-1-PBS in a different storage buffer formulation.

IGFALS Polyclonal Antibody for WB, Indirect ELISA

Cat No. 24545-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

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Product Information

24545-1-PBS targets IGFALS in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: IGFALS fusion protein Ag21696
• Full Name: insulin-like growth factor binding protein, acid labile subunit
• Calculated Molecular Weight: 605 aa, 66 kDa
• Observed Molecular Weight: 85 kDa
• GenBank Accession Number: BC025681
• Gene Symbol: IGFALS
• Gene ID (NCBI): 3483
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P35858
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

THE ACID-LABILE SUBUNIT (ALS), a liver-derived, GH-dependent, 85-kD glycoprotein, is a key component of the 150-kD IGF circulating ternary complex(PMID: 17726072). The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty.