IFNGR1 Monoclonal antibody, PBS Only

IFNGR1 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 66704-1-PBS
Clone No.1H3A4

Host / Isotype

Mouse / IgG2a

Reactivity

human

Applications

WB, Indirect ELISA

IFN-gamma receptor 1, IFN-gamma R1, IFN gamma receptor 1, IFN gamma R1, CD119

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

66704-1-PBS targets IFNGR1 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen IFNGR1 fusion protein Ag27085 Predict reactive species
Full Name interferon gamma receptor 1
Calculated Molecular Weight 54 kDa
Observed Molecular Weight 90 kDa
GenBank Accession NumberBC005333
Gene Symbol IFNGR1
Gene ID (NCBI) 3459
RRIDAB_2882056
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP15260
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Interferon-gamma (IFN-γ) is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Cellular responses to IFN-γ are activated through its interaction with a heterodimeric receptor consisting of two subunits, IFNGR1 (CD119) and IFNGR2. IFNGR1 is the ligand-binding subunit which binds IFN-γ with high affinity, whereas IFNGR2 serves as the accessory subunit. Two subunits bind one IFN-γ dimer. Defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. (PMID: 17981204; 946248; 10888113)

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