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IFNGR1 Monoclonal antibody, PBS Only

IFNGR1 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1H3A4

Cat no : 66704-1-PBS

Synonyms

CD119, CDw119, FLJ45734, IFN gamma R1, IFN gamma receptor 1, IFNGR, IFNGR1, interferon gamma receptor 1

Validation Data Gallery

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  • Western Blot (WB) analysis of HeLa cells using IFNGR1 Monoclonal antibody (66704-1-Ig)

    WB analysis of HeLa using 66704-1-Ig (same clone as 66704-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 66704-1-Ig (IFNGR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66704-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HEK-293 cells using IFNGR1 Monoclonal antibody (66704-1-Ig)

    WB analysis of HEK-293 using 66704-1-Ig (same clone as 66704-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 66704-1-Ig (IFNGR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66704-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of T-47D cells using IFNGR1 Monoclonal antibody (66704-1-Ig)

    WB analysis of T-47D using 66704-1-Ig (same clone as 66704-1-PBS)

    T-47D cells were subjected to SDS PAGE followed by western blot with 66704-1-Ig (IFNGR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66704-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of Jurkat cells using IFNGR1 Monoclonal antibody (66704-1-Ig)

    WB analysis of Jurkat using 66704-1-Ig (same clone as 66704-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 66704-1-Ig (IFNGR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66704-1-PBS in a different storage buffer formulation.

Product Information

66704-1-PBS targets IFNGR1 in WB, Indirect ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen IFNGR1 fusion protein Ag27085
Full Name interferon gamma receptor 1
Calculated Molecular Weight 54 kDa
Observed Molecular Weight 90 kDa
GenBank Accession NumberBC005333
Gene Symbol IFNGR1
Gene ID (NCBI) 3459
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Interferon-gamam (IFN-γ) is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Cellular responses to IFN-γ are activated through its interaction with a heterodimeric receptor consisting of two subunits, IFNGR1 (CD119) and IFNGR2. IFNGR1 is the ligand-binding subunit which binds IFN-γ with high affinity, whereas IFNGR2 serves as the accessory subunit. Two subunits bind one IFN-γ dimer. Defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. (PMID: 17981204; 946248; 10888113)