CoraLite®594-conjugated HRD1/SYVN1 Monoclonal antibody
HRD1/SYVN1 Monoclonal Antibody for IF
Host / Isotype
Mouse / IgG2b
Human, Mouse, Rat
CoraLite®594 Fluorescent Dye
Cat no : CL594-67488
|Positive IF detected in
|IF : 1:50-1:500
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
CL594-67488 targets HRD1/SYVN1 in IF applications and shows reactivity with Human, Mouse, Rat samples.
|Human, Mouse, Rat
|Host / Isotype
|Mouse / IgG2b
|HRD1/SYVN1 fusion protein Ag4456
|synovial apoptosis inhibitor 1, synoviolin
|Calculated molecular weight
|617 aa, 68 kDa
|Observed molecular weight
|GenBank accession number
|Gene ID (NCBI)
|CoraLite®594 Fluorescent Dye
|Excitation/Emission maxima wavelengths
|588 nm / 604 nm
|Protein A purification
|PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
|Store at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
HRD1is also named as SYVN1(Synovial apoptosis inhibitor 1) , KIAA1810. It acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates, promoting their degradation. Two distinct binding sites mediate Hrd1 dimerization or oligomerization, one located within the transmembrane region and another within the cytosolic domain. (PMID:19864457).Western blot analysis detected abundant HRD1 expression in liver and kidney. Mouse liver and spleen expressed Hrd1 as an 85-kD protein(PMID:12646171).