Product Information
10496-1-PBS targets HOXD3 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | HOXD3 fusion protein Ag0768 Predict reactive species |
Full Name | homeobox D3 |
Calculated Molecular Weight | 46 kDa |
GenBank Accession Number | BC005124 |
Gene Symbol | HOXD3 |
Gene ID (NCBI) | 3232 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P31249 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Homeobox D3 (HOXD3), a member of the Homeobox (Hox) family of master transcription factors, is a homeobox transcription factor that promotes angiogenesis and collagen synthesis. HOXD3 is expressed during normal embryogenesis, skin development, and fetal wound healing (PMID: 14633614). The overexpression of HOXD3 plays a critical role in breast cancer stemness and drug resistance via integrin β3-mediated Wnt/β-catenin signaling (PMID: 29698974).