HE4 Monoclonal antibody, PBS Only

HE4 Monoclonal Antibody for IHC, IF/ICC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

IHC, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

5B2D9

Cat no : 66557-1-PBS

Synonyms

HE4, WAP5, WFDC2



Product Information

66557-1-PBS targets HE4 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen HE4 fusion protein Ag5936
Full Name WAP four-disulfide core domain 2
Calculated Molecular Weight 13 kDa
GenBank Accession NumberBC046106
Gene Symbol HE4
Gene ID (NCBI) 10406
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

WFDC2, also named as HE4, is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. HE4 is expressed in a number of normal tissues, and it is also highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. In some study, HE4 was referred to as a biomarker for ovarian carcinoma.