HE4 Monoclonal antibody, PBS Only
HE4 Monoclonal Antibody for IHC, IF/ICC, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
IHC, IF/ICC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
5B2D9
Cat no : 66557-1-PBS
Synonyms
Validation Data Gallery
Product Information
66557-1-PBS targets HE4 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | HE4 fusion protein Ag5936 |
Full Name | WAP four-disulfide core domain 2 |
Calculated Molecular Weight | 13 kDa |
GenBank Accession Number | BC046106 |
Gene Symbol | HE4 |
Gene ID (NCBI) | 10406 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
WFDC2, also named as HE4, is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. HE4 is expressed in a number of normal tissues, and it is also highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. In some study, HE4 was referred to as a biomarker for ovarian carcinoma.