Product Information
82921-1-PBS targets HCRTR1 in WB, Indirect ELISA applications and shows reactivity with human, rat samples.
Tested Reactivity | human, rat |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | HCRTR1 fusion protein Ag12269 Predict reactive species |
Full Name | hypocretin (orexin) receptor 1 |
Calculated Molecular Weight | 425 aa, 48 kDa |
Observed Molecular Weight | 54 kDa |
GenBank Accession Number | BC074796 |
Gene Symbol | HCRTR1 |
Gene ID (NCBI) | 3061 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | O43613 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
The hypocretin receptor 1 (OX1R, also named HCRTR1) is a G protein-coupled receptor and is a critical participant in the regulation of motivated behavior (PMID:28971565). HCRTR1 is associated with the regulation of motivation, reward, and autonomic functions. HCRTR1 shows a selective binding affinity for HCRT1/orexin-A. Moreover, HCRTR1 and HCRTR2 share 64% sequence similarity in humans (PMID:34052813).