HBB Monoclonal antibody, PBS Only

HBB Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, rabbit

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1A11E3

Cat no : 67899-1-PBS

Synonyms

beta globin, CD113t C, HBB, Hemoglobin beta chain, Hemoglobin subunit beta, hemoglobin, beta

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Validation Data Gallery

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  WB analysis using 67899-1-Ig (same clone as 67899-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67899-1-Ig (HBB antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67899-1-PBS in a different storage buffer formulation.

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Product Information

67899-1-PBS targets HBB in WB, Indirect ELISA applications and shows reactivity with Human, rabbit samples.

• Tested Reactivity: Human, rabbit
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: HBB fusion protein Ag9216
• Full Name: hemoglobin, beta
• Calculated Molecular Weight: 147 aa, 16 kDa
• Observed Molecular Weight: 14-16 Da
• GenBank Accession Number: BC007075
• Gene Symbol: HBB
• Gene ID (NCBI): 3043
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein G purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

The hemoglobin molecule is a tetramer consisting of two alpha- and two beta-globin-like chains. HBB gene encodes hemoglobin beta chain. The hemoglobin chains, each with its own heme moiety, cooperate in binding and release of oxygen. Hemoglobin monomers have been found in blood and other tissues including macrophages, alveolar epithelial cells and brain. Defects in HBB have been linked to diseases including Sickle cell anemia, Beta-thalassemia, and Heinz body anemias.