Product Information
67329-1-PBS targets GSK3B in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, pig samples.
Tested Reactivity | human, pig |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | GSK3B fusion protein Ag17320 Predict reactive species |
Full Name | glycogen synthase kinase 3 beta |
Calculated Molecular Weight | 433 aa, 48 kDa |
Observed Molecular Weight | 46-48 kDa |
GenBank Accession Number | BC000251 |
Gene Symbol | GSK3B |
Gene ID (NCBI) | 2932 |
RRID | AB_2882588 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | P49841 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase .GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.In skeletal muscle, it contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Researches showed that the crystal structure of human GSK3B, expressed in insect cells, at 2.8-angstrom resolution .