CoraLite® Plus 647-conjugated GNAS Monoclonal antibody
GNAS Monoclonal Antibody for
Host / Isotype
Mouse / IgG2b
Reactivity
human, pig
Applications
Conjugate
CoraLite® Plus 647 Fluorescent Dye
CloneNo.
1A9C10
Cat no : CL647-66253
Synonyms
Validation Data Gallery
Recommended dilution
Application | Dilution |
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It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
CL647-66253 targets GNAS in applications and shows reactivity with human, pig samples.
Tested Reactivity | human, pig |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | GNAS fusion protein Ag20530 |
Full Name | GNAS complex locus |
Calculated Molecular Weight | 45 kDa |
Observed Molecular Weight | 46 kDa |
GenBank Accession Number | BC002722 |
Gene Symbol | GNAS |
Gene ID (NCBI) | 2778 |
Conjugate | CoraLite® Plus 647 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 654 nm / 674 nm |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 (GNAS1) is the ubiquitously expressed heterotrimeric G protein that couples receptors to the effector enzyme adenylyl cyclase and is required for receptor-stimulated intracellular cAMP generation. Mutations of Gs(alpha) residues involved in the GTPase reaction that lead to constitutive activation are present in endocrine tumors, fibrous dysplasia of bone, and McCune-Albright syndrome. The molecular weight of Gs(alpha) protein is about 46 kDa.
Protocols
Product Specific Protocols | |
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FC protocol for CL Plus 647 GNAS antibody CL647-66253 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |