Product Information
68027-1-PBS targets GNAO1 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with Mouse, Rat, Rabbit, Pig, Chicken, Human samples.
Tested Reactivity | Mouse, Rat, Rabbit, Pig, Chicken, Human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | GNAO1 fusion protein Ag32045 Predict reactive species |
Full Name | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
Calculated Molecular Weight | 302 aa, 35 kDa |
Observed Molecular Weight | 40 kDa |
GenBank Accession Number | BC030027 |
Gene Symbol | GNAO1 |
Gene ID (NCBI) | 2775 |
RRID | AB_2918770 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | P09471 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
GNAO1 gene encodes the α subunit of heterotrimeric guanine nucleotide-binding protein (Gi protein), a membrane protein widely expressed in the central nervous system involved in signal transduction (PMID: 30642806). GNAO1 belongs to the G-alpha family and G(i/o/t/z) subfamily. GNAO1 is highly expressed in brain and modulate neuronal excitability (PMID: 30838255). GNAO1 has 2 isoforms with the molecular mass of 40 kDa.