GGTLC1 Recombinant antibody

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  WB analysis using 83392-3-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 83392-3-RR (GGTLC1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

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  Affinity and Kinetic Characterization of 83392-3-RR

  Biolayer interferometry (BLl) kinetic assays of 83392-3-RR against Human GGTLC1 were performed. The affinity constant is below 1 pM.

GGTLC1 {ptg:Brand} Recombinant Antibody for WB, ELISA

Cat No. 83392-3-RR

Clone No.240297D9

Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

WB, ELISA

Synonyms

GGTLA4, GGTL6, Gamma-glutamyltransferase-like protein 6, Gamma-glutamyltransferase-like activity 4, Gamma-glutamyltransferase light chain 1

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Tested Applications

• Positive WB detected in: HepG2 cells, L02 cells, human urine

Recommended dilution

• Western Blot (WB): WB : 1:500-1:3000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

83392-3-RR targets GGTLC1 in WB, ELISA applications and shows reactivity with Human samples.

• Tested Reactivity: Human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: GGTLC1 fusion protein Ag11592
• Full Name: gamma-glutamyltransferase light chain 1
• Calculated Molecular Weight: 225 aa, 24 kDa
• Observed Molecular Weight: 20-24 kDa
• GenBank Accession Number: BC040904
• Gene Symbol: GGTLC1
• Gene ID (NCBI): 92086
• RRID: AB_3671046
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q9BX51
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Gamma-glutamyltransferase light chain 1 (GGTLC1), initially named GGTL6, then GGTLA4, and later GGTLC1 in 2008, is a member of the gamma-glutamyl transferase (GGT) family. The most ubiquitously expressed human GGT gene, GGT1, encodes a single transmembrane polypeptide that is post-translationally processed to form a heavy and a light chain. Knockdown of GGTLC1 in Endometrial cancer (EC) cells was shown to induce G0/G1 phase arrest and apoptosis, underscoring the significance of GGTLC1 as a key regulator of these cellular processes in EC (PMID: 38841516).