GATM Monoclonal antibody, PBS Only

GATM Monoclonal Antibody for WB, Indirect ELISA
Cat No. 68513-1-PBS
Clone No.1D12G5

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat, pig

Applications

WB, Indirect ELISA

Transamidinase, L-arginine:glycine amidinotransferase, EC:2.1.4.1, AGAT, 1D12G5

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

68513-1-PBS targets GATM in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig samples.

Tested Reactivity human, mouse, rat, pig
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen GATM fusion protein Ag3754 Predict reactive species
Full Name glycine amidinotransferase (L-arginine:glycine amidinotransferase)
Calculated Molecular Weight 423 aa, 48 kDa
Observed Molecular Weight48 kDa
GenBank Accession NumberBC004141
Gene Symbol GATM
Gene ID (NCBI) 2628
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP50440
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

GATM, also known as AGAT, produces ornithine and guanidinoacetate (GAA) from arginine and glycine, and is a key enzyme for creatine synthesis. GATM deficiency in early infancy causes neurodevelopmental delay. GATM is predominantly expressed in kidney and pancreas in adults. Decrease of GAMT proteins was observed in proximal tubule damage cases, which links GATM as a general marker for proximal tubule damage. Alternative splicing of GATM generates three isoforms with molecular weights between 44 kDa to 48 kDa.

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