GAMT Monoclonal antibody

GAMT Monoclonal Antibody for WB, ELISA
Cat No. 66322-1-Ig
Clone No.1E7B11

Host / Isotype

Mouse / IgG2a

Reactivity

human, rat, mouse, pig

Applications

WB, ELISA

GAMT, PIG2, TP53I2

Formulation:  PBS and Azide
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Tested Applications

Positive WB detected infetal human brain tissue, mouse liver tissue, pig liver tissue, rat liver tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

66322-1-Ig targets GAMT in WB, ELISA applications and shows reactivity with human, rat, mouse, pig samples.

Tested Reactivity human, rat, mouse, pig
Cited Reactivityhuman, mouse
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen GAMT fusion protein Ag16778 Predict reactive species
Full Name guanidinoacetate N-methyltransferase
Calculated Molecular Weight 26 kDa
Observed Molecular Weight 26 kDa
GenBank Accession NumberBC016760
Gene Symbol GAMT
Gene ID (NCBI) 2593
RRIDAB_2881702
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ14353
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

GAMT converts the latter to creatine with S-adenosylmethionine as the methyl donor. GAMT was induced in human and mouse cells in response to genotoxic and metabolic stress. GAMT was required for p53-dependent upregulation of creatine biosynthesis, fatty acid oxidation, and apoptosis in response to glucose deprivation.

Protocols

Product Specific Protocols
WB protocol for GAMT antibody 66322-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseWB

Food Funct

The protective effect of polyunsaturated fatty acid intake during pregnancy against embryotoxicity of sodium valproate in mice

Authors - Kelei Li
humanWB

BMC Cardiovasc Disord

PMID: 31888640

Authors - Zhuyin Jia
mouseWB

Sci Rep

Intratesticular creatine maintains spermatogenesis by defining tight junctions

Authors - Sohei Kuribayashi
  • KO Validated
humanWB

Sci Rep

Identification of disulfidptosis-related subtypes in gastric cancer and GAMT is a key gene during disulfidptosis

Authors - Wenxue Wu
  • KD Validated
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