Product Information
13671-1-PBS targets GALNT6 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | GALNT6 fusion protein Ag4652 Predict reactive species |
Full Name | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) |
Calculated Molecular Weight | 622 aa, 71 kDa |
Observed Molecular Weight | 71 kDa |
GenBank Accession Number | BC035822 |
Gene Symbol | GALNT6 |
Gene ID (NCBI) | 11226 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q8NCL4 |
Storage Buffer | PBS only , pH 7.3 |
Storage Conditions | Store at -80°C. |
Background Information
GALNT6 (polypeptide N-acetylgalactosaminyltransferase 6, GalNAc-T6), which is involved in the initiation of O-glycosylation, has been reported to play crucial roles in mammary carcinogenesis through binding to several substrates (PMID: 32393740). GALNT6 is upregulated in breast, ovarian, renal cell, lung and pancreatic cancers (PMID: 20215525). Overexpression of GRP78 could enhance Golgi-to-ER relocation of GALNT6 (PMID: 28110670).