Product Information
29992-1-PBS targets Fibulin 5 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Fibulin 5 fusion protein Ag30835 Predict reactive species |
Full Name | fibulin 5 |
Calculated Molecular Weight | 448 aa, 50 kDa |
Observed Molecular Weight | 65-70 kDa |
GenBank Accession Number | BC022280 |
Gene Symbol | Fibulin 5 |
Gene ID (NCBI) | 10516 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q9UBX5 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Fibulin-5, also known as EVEC and DANCE, is an extracellular matrix glycoprotein, secreted by various cell types such as vascular smooth muscle cells, fibroblasts and endothelial cells. Structurally, Fibulin-5 contains an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. FBLN5 mutations have been described in patients with age-related macular degeneration, as well as being involved in Charcot-Marie-Tooth neuropathies.