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Fas/CD95 Polyclonal antibody, PBS Only

Fas/CD95 Polyclonal Antibody for WB, IP, Indirect ELISA
Cat No. 13098-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IP, Indirect ELISA

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

13098-1-PBS targets Fas/CD95 in WB, IP, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Fas/CD95 fusion protein Ag3718 Predict reactive species
Full Name Fas (TNF receptor superfamily, member 6)
Calculated Molecular Weight 35-38 kDa
Observed Molecular Weight 38-45 kDa
GenBank Accession NumberBC012479
Gene Symbol Fas/CD95
Gene ID (NCBI) 355
RRIDAB_2278042
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP25445
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediate apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The molecular mass of native Fas is 38 kDa, the high molecular weight form (40-55 kDa) of Fas is due to glycosylation.

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