CoraLite® Plus 488-conjugated FSHB Monoclonal antibody

FSHB Monoclonal Antibody for IF/ICC

Host / Isotype

Mouse / IgG2b

Reactivity

human

Applications

IF/ICC

Conjugate

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

1B10A11

Cat no : CL488-67131

Synonyms

FSH beta, FSH B, Follitropin subunit beta, Follitropin beta chain, Follicle-stimulating hormone beta subunit



Tested Applications

Positive IF/ICC detected inHepG2 cells

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL488-67131 targets FSHB in IF/ICC applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen FSHB fusion protein Ag13788
Full Name follicle stimulating hormone, beta polypeptide
Calculated Molecular Weight 129 aa, 15 kDa
Observed Molecular Weight 15 kDa
GenBank Accession NumberBC113488
Gene Symbol FSHB
Gene ID (NCBI) 2488
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

The FSHB gene encodes the beta subunit of follicle-stimulating hormone (FSH), particularly expressed in gonadotroph cells within the anterior pituitary gland and plays a critical role in the regulation of gonadal function, pubertal maturation and reproductive processes in mammals. The transcription of the FSHB gene is critical for the production of the FSH hormone(PMID:28281143). And FSH is required for ovarian folliculogenesis in females, in males it promotes spermatogenesis in conjunction with testosterone(PMID:11739331). Mutations in FSHB gene would result in infertility both in men and women (PMID: 23766128).

Protocols

Product Specific Protocols
IF protocol for CL Plus 488 FSHB antibody CL488-67131Download protocol
Standard Protocols
Click here to view our Standard Protocols