FOXL2-Specific Recombinant antibody

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  WB analysis using 84144-1-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 84144-1-RR (FOXL2-Specific antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

FOXL2-Specific {ptg:Brand} Recombinant Antibody for WB, ELISA

Cat No. 84144-1-RR

Clone No.240904F7

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Synonyms

FOXL2, PINTO, PFRK, BPES1, BPES

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Tested Applications

• Positive WB detected in: mouse ovary tissue, rat ovary tissue

Recommended dilution

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

84144-1-RR targets FOXL2-Specific in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Peptide
• Full Name: forkhead box L2
• Calculated Molecular Weight: 39 kDa
• Observed Molecular Weight: 45-50 kDa
• GenBank Accession Number: NM_023067
• Gene Symbol: FOXL2
• Gene ID (NCBI): 668
• RRID: AB_3671706
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: P58012
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

FOXL2 is a critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. It prevents trans-differentiation of ovary to testis through transcriptional repression of the sertoli cell-promoting gene SOX9. FOXL2 is mainly expressed in ovary, parathyroid gland and sex cord-stromal tumors.