Product Information
84144-1-PBS targets FOXL2-Specific in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | Peptide Predict reactive species |
Full Name | forkhead box L2 |
Calculated Molecular Weight | 39 kDa |
Observed Molecular Weight | 45-50 kDa |
GenBank Accession Number | NM_023067 |
Gene Symbol | FOXL2 |
Gene ID (NCBI) | 668 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | P58012 |
Storage Buffer | PBS only , pH 7.3 |
Storage Conditions | Store at -80°C. |
Background Information
FOXL2 is a critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. It prevents trans-differentiation of ovary to testis through transcriptional repression of the sertoli cell-promoting gene SOX9. FOXL2 is mainly expressed in ovary, parathyroid gland and sex cord-stromal tumors.