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FGF18 Monoclonal antibody, PBS Only

FGF18 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse, rabbit

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1D11D12

Cat no : 60341-1-PBS

Synonyms

FGF 18, FGF18, fibroblast growth factor 18, ZFGF5

Validation Data Gallery

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  • Western Blot (WB) analysis of HT-1080 cells using FGF18 Monoclonal antibody (60341-1-Ig)

    WB analysis of HT-1080 using 60341-1-Ig (same clone as 60341-1-PBS)

    HT-1080 cells were subjected to SDS PAGE followed by western blot with 60341-1-Ig (FGF18 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60341-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of NIH/3T3 cells using FGF18 Monoclonal antibody (60341-1-Ig)

    WB analysis of NIH/3T3 using 60341-1-Ig (same clone as 60341-1-PBS)

    NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 60341-1-Ig (FGF18 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60341-1-PBS in a different storage buffer formulation.

Product Information

60341-1-PBS targets FGF18 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rabbit samples.

Tested Reactivity human, mouse, rabbit
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen FGF18 fusion protein Ag2041
Full Name fibroblast growth factor 18
Calculated Molecular Weight 207 aa, 24 kDa
Observed Molecular Weight 21 kDa
GenBank Accession NumberBC006245
Gene Symbol FGF18
Gene ID (NCBI) 8817
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

FGF18 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.