Product Information
60341-1-PBS targets FGF18 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rabbit samples.
Tested Reactivity | human, mouse, rabbit |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | FGF18 fusion protein Ag2041 Predict reactive species |
Full Name | fibroblast growth factor 18 |
Calculated Molecular Weight | 207 aa, 24 kDa |
Observed Molecular Weight | 21 kDa |
GenBank Accession Number | BC006245 |
Gene Symbol | FGF18 |
Gene ID (NCBI) | 8817 |
RRID | AB_2881450 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | O76093 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
FGF18 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.